Introduction
Chronic Kidney Disease (CKD) Stage III, also known as Stage 3 Chronic Kidney Disease, is a moderate stage of kidney disease in which the kidneys are no longer filtering blood as efficiently as they should. Although the kidneys continue to function, waste products and excess fluids may begin to accumulate in the body, increasing the risk of complications if left untreated.
The good news is that CKD Stage III can often be managed successfully with early diagnosis, proper medical treatment, healthy lifestyle changes, and regular follow-up with a nephrologist. Timely intervention can help slow disease progression, preserve remaining kidney function, and reduce the likelihood of kidney failure.
At Prabhakar Bhurke Clinic, our super specialist nephrologist offers comprehensive diagnosis, individualized treatment, and long-term management for patients with CKD Stage III using the latest evidence-based medical practices.
What Is CKD Stage III?
Chronic Kidney Disease is classified into five stages based on the Estimated Glomerular Filtration Rate (eGFR), which measures how effectively the kidneys filter waste from the blood.
CKD Stage III is divided into:
Stage 3A
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eGFR: 45–59 mL/min/1.73 m²
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Mild to moderate reduction in kidney function.
Stage 3B
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eGFR: 30–44 mL/min/1.73 m²
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Moderate to severe reduction in kidney function with a higher risk of complications.
Although kidney damage is significant at this stage, many patients do not require dialysis. Early treatment is aimed at preserving kidney function and preventing progression to advanced stages.
Common Causes of CKD Stage III
Several health conditions can contribute to the development of Stage III CKD, including:
Diabetes
High blood sugar can damage the tiny blood vessels in the kidneys over time, leading to diabetic kidney disease.
High Blood Pressure
Uncontrolled hypertension is one of the leading causes of chronic kidney damage.
Glomerulonephritis
Inflammation of the kidney's filtering units can gradually reduce kidney function.
Polycystic Kidney Disease (PKD)
This inherited disorder causes multiple cysts to develop in the kidneys, affecting their ability to function.
Recurrent Kidney Infections
Repeated infections can cause kidney scarring and long-term damage.
Urinary Tract Obstruction
Conditions such as kidney stones or an enlarged prostate may interfere with urine flow and damage the kidneys if left untreated.
Autoimmune Diseases
Diseases such as lupus can affect the kidneys and contribute to chronic kidney disease.
Symptoms of CKD Stage III
Many people with Stage III CKD have few or no symptoms initially. As kidney function declines, symptoms may include:
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Persistent fatigue
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Swelling of the feet, ankles, hands, or face
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High blood pressure
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Frequent urination, especially at night
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Foamy urine
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Blood in the urine
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Muscle cramps
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Dry or itchy skin
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Loss of appetite
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Nausea
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Difficulty concentrating
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Mild back or flank discomfort
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Weakness
Because symptoms can be subtle, regular kidney screening is essential for individuals at risk.
Complications of CKD Stage III
Without appropriate treatment, CKD Stage III may lead to:
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Progression to





